MAMMAL Inference API

IBM biomed.omics.bl.sm.ma-ted-458m + finetuned task checkpoints, served by CureCancerWithAI.

Authentication

Every inference endpoint requires a bearer API key. Call the API server-side only — never expose the key to a browser.

Authorization: Bearer <YOUR_MAMMAL_API_KEY>

Endpoints

Endpoint	Task	Input	Output
`POST /ppi`	Protein–protein binding-affinity class	two amino-acid sequences	`{"prediction": "..."}`
`POST /dti`	Drug–target binding affinity (pKd)	target AA sequence + drug SMILES	`{"pKd": float}`
`POST /clintox_tox`	ClinTox clinical-trial toxicity	drug SMILES	`{"pred": 0\|1, "score": float}`
`GET /health` no key	Liveness + loaded models	—	`{"status":"ok", ...}`

Examples

Drug–target interaction (pKd)

curl -X POST https://mammal.curecancerwithai.com/dti \
  -H "Authorization: Bearer $MAMMAL_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"target_seq":"NLMKRCTRGFRKLGKCTTLEEEKCKTLYPRGQCTCSDSKMNTHSCDCKSC","drug_seq":"CC(=O)NCCC1=CNc2c1cc(OC)cc2"}'
# -> {"pKd": 5.49}

ClinTox clinical-trial toxicity

curl -X POST https://mammal.curecancerwithai.com/clintox_tox \
  -H "Authorization: Bearer $MAMMAL_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"smiles":"CC(CCl)OC(C)CCl"}'
# -> {"pred": 0, "score": 1.9e-05}

Protein–protein interaction

curl -X POST https://mammal.curecancerwithai.com/ppi \
  -H "Authorization: Bearer $MAMMAL_API_KEY" \
  -H "Content-Type: application/json" \
  -d '{"protein_a":"MADQLTEEQ...","protein_b":"MSSKLLLAG..."}'

For interactive request building and the full schema, see /docs or /redoc.